Home

About

Director

News and Reports

Seminars

Research Groups

Immunology
(Cezmi Akdis)

Immune Metabolism
(Milena Sokolowska)

Dermatology
(Mübeccel Akdis)

Molecular Allergology
(Katja Bärenfaller)

Molecular Immunology
(Liam O‘Mahony)

Vaccine Development
(Claudio Rhyner)

Publications

International Networks

Diagnostic Routine

Gallery

PhD/Jobs

WIRM

Head: Liam O‘Mahony
Degree: PD, Ph.D.


Phone: +41 (0) 81 410 08 53
E-mail: liam.omahony(a)siaf.uzh.ch

Group members:
  1. Ruth Ferstl
  2. Remo Frei

Molecular Immunology

 

Molecular Immunology

The immune response is a tightly regulated process which normally results in protection from infection and tolerance of innocuous environmental antigens.  However, in allergic disease, the activated immune response results in a chronic pro-inflammatory state characterized by antibody secretion (IgE) and T cell activation to normally well-tolerated antigens.  The role played by microbial and allergen activated dendritic cells in these phenomena is not well understood in allergic patients. 

Our group is examining the molecular mechanisms and clinical importance of Toll-like Receptors (TLRs) and C-type Lectin Receptors (CLRs) activation by microbial components in dendritic cells from patients with allergy and asthma.

 

Publications

Pubmed search